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  Photoacoustic Imaging


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    Image reconstruction

    Photoacoustic propagation     models

    Quantitative photoacoustic     spectroscopy

  Optical Ultrasound Detection

    Guide to FP ultrasound sensing

    Fibre optic hydrophone

    2D ultrasound array

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    UCL Dept of Medical Physics &     Bioengineering




 Photoacoustic Imaging Group                                                BORL

Latest 3D photoacoustic images - to see more and find out how these were obtained, click here

The Photoacoustic Imaging Goup was founded in 2002 and forms a sub-group of the UCL Biomedical Optics Research Laboratory, BORL. It currently comprises 17 researchers, funded through a combination of UK research council grants and industrial sponsorship. Our activities are directed towards the development of a promising new method of non-invasive biomedical imaging based upon the use of laser-generated acoustic waves for visualising the internal structure and function of soft tissues. Potential applications include the clinical assessment of breast cancer, vascular disease and skin abnormalities. The technique also has important applications as a research tool in the basic life sciences for undertaking molecular and genomic imaging studies, for example studying tumour physiology. Our current research encompasses the full range of activities in photoacoustic methods: photoacoustic detection and excitation instrumentation, modelling of photoacoustic signals, image reconstruction algorithms, spectroscopic methods and the application of the technique in the clinical and life sciences.

In addition to biomedical photoacoustic imaging, a range of ultrasound field measurement and imaging tools based upon the use of Fabry Perot polymer film sensing interferometers is being developed. These include a miniature wideband fibre optic hydrophone for characterising medical and industrial ultrasound fields and high speed 2D arrays for field visualisation and imaging applications in medicine and industrial NDT.


Latest additions

star4star3 Postdoctoral research positions available star2star1 further details to follow

k-Wave - a Matlab toolbox for the simulation of photoacoustic and ultrasound fields


Recently published articles:

Stahl T, Bofinger R, Lam I, Fallon KJ, Johnson P, Ogunlade O, Vassileva V, Pedley RB, Beard PC, Hailes HC, Bronstein H, Tabor AB (2017), Tunable Semiconducting Polymer Nanoparticles with INDT-Based Conjugated Polymers for Photoacoustic Molecular Imaging, Bioconjugate Chemistry 28 (6) 1734-1740 Download PDF file

Xia W, West SJ, Finlay M, Mari J-M, Ourselin S, David AL, Desjardins AE (2017), Looking beyond the imaging plane: 3D needle tracking with a linear array ultrasound probe, Scientific Reports 7 3674-3682. Download PDF file

Poduval RK, Noimark S, Colchester RJ, Macdonald TJ, Parkin IP, Desjardins AE, Papakonstantinou I (2017), Optical fiber ultrasound transmitter with electrospun carbon nanotube-polymer composite, Appl. Phys. Lett. 110 223701 doi: 10.1063/1.4984838 Download PDF file

Alles EJ, Fook Sheung N, Noimark S, Zhang EZ, Beard PC and Desjardins AE, A reconfigurable all-optical ultrasound transducer array for 3D endoscopic imaging (2017), Scientific Reports 7 1208 Download PDF file

Arridge S, Beard P, Betcke M, Cox B, Huynh N, Lucka F, Ogunlade O and Zhang E (2016), Accelerated High-Resolution Photoacoustic Tomography via Compressed Sensing, Phys Med Biol 61(24) 8908-8940 doi:10.1088/1361-6560/61/24/8908 Download PDF file

Schneider C, Johnson SP, Gurusamy K, Cook RJ, Desjardins AE, Hawkes DJ, Davidson BR and Walker-Samuel S (2017), Identification of liver metastases with probe-based confocal laser endomicroscopy at two excitation wavelengths, Lasers in Surgery and Medicine doi:10.1002/lsm.22617 Download PDF file

Hill ER, Xia W, Clarkson MJ, and Desjardins AE (2016), Identification and removal of laser-induced noise in photoacoustic imaging using singular value decomposition, Biomedical Optics Express 8(1) Download PDF file

Noimark S, Colchester RJ, Blackburn BJ, Zhang EZ, Alles EJ, Ourselin S, Beard PC, Papakonstantinou I, Parkin IP and Desjardins AE (2016), Carbon-Nanotube-PDMS Composite Coatings on Optical Fibers for All-Optical Ultrasound Imaging, Advanced Functional Materials doi:10.1002/adfm.201601337 Download PDF file

Alles EJ, Noimark S, Zhang E, Beard PC, Desjardins AE (2016), Pencil beam all-optical ultrasound imaging, Biomedical Optics Express 7(9) 3696-3704 Download PDF file

Schneider C, Johnson SP, Walker-Samuel S, Gurusamy K, Clarkson MJ, Thompson S, Song Y, Totz J, Cook RJ, Desjardins AE, Hawkes DJ, Davidson (2016), Utilizing confocal laser endomicroscopy for evaluating the adequacy of laparoscopic liver ablation, Lasers in Surgery and Medicine 48(3) 299-310 Download PDF file

Mazomenos EB, Chang P-L, Rippel RA, Rolls A, Hawkes DJ, Bicknell CD, Desjardins A, Riga CV, Stoyanov D (2016), Catheter manipulation analysis for objective performance and technical skills assessment in transcatheter aortic valve implantation, International Journal of Computer Assisted Radiology and Surgery 11(6) 1121-31 Download PDF file

Nam H, Zhang EZ, Betcke M, Arrridge S, Beard PC, Cox B (2016), Single-Pixel Optical Camera for Video Rate Ultrasonic Imaging, Optica 3(1) 26-29 Download PDF file

Brunker B, Beard PC (2016), Velocity measurements in whole blood using acoustic resolution photoacoustic Doppler, Biomedical Optics Express 7(7) 2789-2806 Download PDF file

Fonseca M, Zeqiri B, Beard PC, Cox BT (2016), Characterisation of a phantom for multiwavelength quantitative photoacoustic imaging, Physics in Medicine and Biology 61(13) 4950-4973. Download PDF file

Xia W, Ginsberg Y, West SJ, Nikitichev DI, Ourselin S, David AL, Desjardins AE (2016), Coded excitation ultrasonic needle tracking: An in vivo study, Medical Physics 43(7) 4065-73 Download PDF file

For a full list of publications, click here


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